Existing Host Range Mutations Constrain Further Emergence of RNA Viruses
نویسندگان
چکیده
منابع مشابه
Mutations of Bacterial Viruses Affecting Their Host Range.
W HEN susceptible bacteria are spread on a solid culture medium with a large amount of a bacterialvirus, complete lysis occurs after incubation, except for the appearance in some cases of colonies consisting of virus-resistant cells. These are the descendants of bacteria that had undergone a mutation from virus-sensitivity to virus-resistance prior to the action of the virus (LURI.A and DELBRUC...
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The ability of a virus population to colonize a novel host is predicted to depend on the equilibrium frequency of potential colonists (i.e., genotypes capable of infecting the novel host) in the source population. In this study, we investigated the determinants of the equilibrium frequency of potential colonists in the RNA bacteriophage 6. We isolated 40 spontaneous mutants capable of infecting...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2019
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.01385-18